Manufacturer: Wockhardt Ltd
Salt Composition : Bromhexine(4mg), Guaifenesin(50mg), Menthol(2.5mg), Terbutaline(1.25mg)
Bro-Zedex Syrup is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
Bro-Zedex syrup works by the combined action of its components: terbutaline, guaifenesin and bromhexine. Terbutaline has bronchodilator properties. It relaxes the muscles of the airways and inhibits the release of inflammation-causing chemical substances.
Bromhexine hydrochloride is rapidly absorbed from the gastrointestinal tract and undergoes extensive first-pass metabolism in the liver. Its oral bioavailability is stated to be only about 20%. It is widely distributed to body tissues and is highly bound to plasma proteins.Guaifenesin is administered orally. The plasma half-life is approximately 1 hour. Guiafenesin is rapidly hydrolyzed (60% within seven hours) and then excreted in the urine, with beta-(2-methoxyphenoxy)-lactic acid as its major urinary metabolite. No unchanged drug was detected in the urine following administration.Menthol is a selective activator of transient receptor potential melastatin- 8 (TRPM8) channels and is also a vasoactive compound. As a topical agent, it acts as a counter- irritant by imparting a cooling effect and by initially stimulating nociceptors and then desensitizing them.The pharmacokinetics of terbutaline has been studied after subcutaneous adminsitration of a therapeutic dose of 250 microgram in 14 patients. Short absorption half-lives of about 7 min resulted in a fast uptake of the drug.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bro-Zedex
Nausea
Indigestion
Bloating
Vomiting
Diarrhea
Stomach pain
Dizziness
Headache
Sweating
Skin rash
Hives
Tremors
Increased heart rate
Palpitations
Hypersensitivity to Bro Zedex Syrup is a contraindication. In addition, Bro Zedex Syrup should not be used if you have the following conditions:
Allergic reactions
Breastfeeding
Breathing difficulty
History of allergy to Ambroxol or Bromhexine
Pregnant
Taking more than one cough or cold medicine
Bro-Zedex Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
It is not known whether it is safe to consume alcohol with Bro-Zedex Syrup. Please consult your doctor.
Information regarding the use of Bro-Zedex Syrup during breastfeeding is not available. Please consult your doctor.
Use with caution
Below 9years: Contraindicated
Bromhexine+Guaifenesin+Menthol+Terbutaline is used in the treatment of cough.Bromhexine is a mucolytic which thins and loosens mucus (phlegm), making it easier to cough out. Guaifenesin is an expectorant which works by decreasing the stickiness of airway secretions and helps in their removal from the airways. Menthol is an organic compound which produces a sensation of coolness and relieves minor throat irritation. Terbutaline is a bronchodilator which relaxes the muscles in the airways and widens the airways.Together, they make breathing easier.
If you use other drugs or over the counter products at the same time, the effects of Bro Zedex Syrup may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Bro Zedex Syrup may interact with the following drugs and products:
Antibiotics
Bendroflumethiazide
Carvedilol
Nadolol
Sotalol
Timolol
Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Bro-Zedex Syrup may be taken with or without food, but it is better to take it at a fixed time.
Store below 30°C
If you miss a dose of Bro-Zedex Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Consult a doctor before taking any medicines.
Bro-Zedex Syrup relieves cough associated with bronchitis, bronchial asthma, emphysema and other broncho-pulmonary disorders.
It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
If you are diabetic, monitor your blood glucose regularly while taking this medicine.
Inform your doctor if you have a history of thyroid or heart disease.
Stop taking Bro-Zedex Syrup and inform your doctor if your cough persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache.
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Bro-Zedex Syrup may be taken with or without food, but it is better to take it at a fixed time.
Q. What are the instructions for the storage and disposal of Bro-Zedex Syrup?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. Can I take Bro-Zedex Syrup along with other medicines?
Inform your doctor about the medicines you might be taking before using Bro-Zedex Syrup. Let your doctor know if you have any other medical condition.
Q. Will a higher than the recommended dose of Bro-Zedex Syrup be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms, that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
